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Simple muscle relaxation may reduce pain and anxiety in uterine biopsy

NCT ID NCT07694037

Symptom relief Sponsor: Uskudar University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study investigates whether performing progressive muscle relaxation exercises before an endometrial biopsy can help reduce pain, lower anxiety, and improve comfort in premenopausal women. Participants will be women aged 40 or older with irregular cycles who need this biopsy. The approach involves a behavioral intervention—guided muscle relaxation—compared to standard care, with outcomes measured using pain scales, anxiety questionnaires, and comfort assessments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
progressive muscle relaxation exercise
What this could lead to
If effective, this simple relaxation technique could become a low-cost, drug-free way to reduce pain and anxiety during endometrial biopsy.
What could go wrong
This is a small, single-center study with 62 participants. The results may not apply to all women, and the exercise may not significantly reduce pain or anxiety for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Started

Apr 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 55 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Endometrial biopsy request must be performed using an endometrial biopsy cannula (Pipelle). * Aged 40 years or older with irregular cycles. * At least a primary school graduate. * No impediment to performing progressive relaxation exercises. * The patient's consent to participate in the study. Exclusion Criteria: * Presence of any physical or mental disability. * The patient's refusal to participate in the study. * Presence of any neurological or psychiatric disorder/use of medication * Having entered menopause. * Having a disease that could prevent the exercises from being performed (musculoskeletal problems, asthma, etc.). * The patient having previously undergone an abortion, endometrial biopsy, or endocervical biopsy.

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Conditions

The condition(s) this trial relates to.

anxiety disorder endometrial disorder Pain uterine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometrial diseases

Contacts and locations

Locations

  • Istanbul Esenyurt Necmi Kadıoğlu State Hospital

    Istanbul, Esenyurt, 3434, Turkey (Türkiye)

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