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New drug combo shows promise in early brain cancer trial

NCT ID NCT06095375

First seen Jan 11, 2026 · Last updated May 01, 2026 · Updated 21 times

Summary

This early-stage study tested adding the drug regorafenib to standard chemotherapy and radiation for people with a specific type of aggressive brain cancer (glioblastoma). The goal was to find a safe dose and see if the combination is tolerable. 21 adults with newly diagnosed, MGMT-methylated glioblastoma took part. The study focused on side effects and finding the right dose, not yet on curing the disease.

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Contacts and locations

Locations

  • Humanitas Research Hospital

    Rozzano, 20089, Italy

  • Istituto Oncologico Veneto IRCCS

    Padova, 35128, Italy

Conditions

Explore the condition pages connected to this study.