MGMT-METHYLATED GLIOBLASTOMA
Clinical trials for MGMT-METHYLATED GLIOBLASTOMA explained in plain language.
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Promising combo therapy for aggressive brain cancer enters final testing phase
Disease control Recruiting nowThis Phase 3 trial tests whether adding lomustine to standard temozolomide chemotherapy improves survival for people with newly diagnosed glioblastoma that has a specific genetic marker (MGMT methylated). About 200 adults aged 18-70 will be randomly assigned to receive either the…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE3 • Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated Jun 22, 2026 12:01 UTC
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Could a common drug shield the brain from Chemo-Radiation damage in glioblastoma?
Disease control Recruiting nowThis study tests whether giving G-CSF (a drug that boosts white blood cells) during standard chemoradiation can help preserve brain volume and thinking abilities in people with a specific type of glioblastoma (MGMT-methylated). About 60 newly diagnosed patients will be randomly a…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 18, 2026 11:46 UTC
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New hope for brain cancer: experimental virus therapy targets aggressive tumors
Disease control Recruiting nowThis study tests whether adding two experimental drugs, DB107-RRV and DB107-FC, to standard treatment (radiation and chemotherapy) can help people with newly diagnosed high grade glioma, a fast-growing brain cancer. About 70 adults aged 18-75 will receive the drugs during and aft…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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Could a new combo therapy extend life in aggressive brain cancer?
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to standard treatment (radiation and temozolomide) helps people with newly diagnosed glioblastoma live longer. About 190 adults will be randomly assigned to receive either the standard treatment alone or standard treatment plus…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Baptist Health South Florida • Aim: Disease control
Last updated Jun 11, 2026 12:11 UTC