MGMT-METHYLATED GLIOBLASTOMA
Clinical trials for MGMT-METHYLATED GLIOBLASTOMA explained in plain language.
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Promising drug cocktail takes on deadly brain tumor
Disease control Recruiting nowThis study tests whether adding lomustine to standard temozolomide chemotherapy helps people with a specific type of glioblastoma live longer. It includes 200 adults aged 18-70 with newly diagnosed, MGMT-methylated tumors. Participants are randomly assigned to standard chemo or t…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE3 • Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated May 01, 2026 17:42 UTC
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Brain cancer trial tests G-CSF to shield thinking skills
Disease control Recruiting nowThis study tests whether a drug called G-CSF (filgrastim) can help preserve brain structure and thinking abilities in people with a specific type of glioblastoma (MGMT-methylated) who are receiving standard chemotherapy and radiation. About 60 participants will be randomly assign…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Could a new drug combo extend life in aggressive brain cancer?
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to standard treatment (radiation and temozolomide) helps people with newly diagnosed glioblastoma live longer. About 190 adults will be randomly assigned to receive either the standard treatment alone or standard treatment plus…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Baptist Health South Florida • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC