MGMT-METHYLATED GLIOBLASTOMA
Clinical trials for MGMT-METHYLATED GLIOBLASTOMA explained in plain language.
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Experimental combo therapy targets aggressive brain cancer in early trial
Disease control Recruiting nowThis study tests whether adding two experimental drugs, DB107-RRV and DB107-FC, to standard treatment (radiation and chemotherapy) helps people with newly diagnosed high grade glioma, a fast-growing brain tumor. About 70 adults aged 18-75 will receive the drugs during surgery and…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 26, 2026 11:15 UTC
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Could a new drug combo extend lives in aggressive brain cancer?
Disease control Recruiting nowThis study tests whether adding the drug ruxolitinib to standard treatment (radiation and temozolomide) helps people with newly diagnosed glioblastoma live longer. About 190 adults will be randomly assigned to receive either the standard treatment alone or standard treatment plus…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Baptist Health South Florida • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New hope for recurrent brain cancer? drug combo trial launches
Disease control Recruiting nowThis study tests a new drug (selinexor) added to standard chemotherapy (temozolomide) for people with glioblastoma that has returned after initial treatment. The goal is to see if the combination is safe and works better than chemotherapy alone to shrink or stabilize the tumor. A…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Could a common drug shield the brain from chemo-radiation damage in glioblastoma?
Disease control Recruiting nowThis study tests whether giving G-CSF (a drug that boosts white blood cells) during standard chemoradiation can help preserve brain structure and thinking abilities in people with a specific type of glioblastoma (MGMT-methylated). About 60 newly diagnosed patients will be randoml…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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Promising new combo may extend life in aggressive brain cancer
Disease control Recruiting nowThis study tests whether adding another chemotherapy drug (lomustine) to the standard treatment can help people with a specific type of glioblastoma, a fast-growing brain cancer, live longer. About 200 adults aged 18-70 with newly diagnosed, MGMT-methylated glioblastoma will be r…
Matched conditions: MGMT-METHYLATED GLIOBLASTOMA
Phase: PHASE3 • Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated May 13, 2026 15:58 UTC