New combo therapy tested against aggressive brain tumor

NCT ID NCT06095375

First seen Jan 11, 2026 · Last updated Apr 28, 2026 · Updated 20 times

Summary

This early-phase study tested adding the drug regorafenib to standard chemotherapy and radiation for people with a specific type of newly diagnosed glioblastoma (a fast-growing brain cancer). The goal was to find the safest dose of regorafenib when used with standard treatment. 21 adults took part. The study focused on side effects and drug levels, not on curing the disease.

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Contacts and locations

Locations

  • Humanitas Research Hospital

    Rozzano, 20089, Italy

  • Istituto Oncologico Veneto IRCCS

    Padova, 35128, Italy

Conditions

Explore the condition pages connected to this study.