Plastic-Free diet shows promise for heart health
NCT ID NCT06571994
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether avoiding plastic in food, personal care, and cleaning products can lower levels of plastic-related chemicals in the body and improve health markers in adults with heart disease risk factors. Sixty participants either followed a low-plastic lifestyle for four weeks or continued as usual. Researchers measured chemical levels in urine and other health indicators to see if reducing plastic exposure makes a difference.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Biological males or, non-pregnant, non-lactating biological females aged 18 to 60 years. a) For female participants at least one of the following must apply: i) Not of childbearing potential - surgical sterile or postmenopausal (no menses last 12 months and follicle-stimulating hormone (FSH) greater than 40 mIU/mL); ii) Childbearing potential and agrees to practice true abstinence, is in a same-sex relationship or agrees to use effective contraception during the study (either hormonal contraception, intrauterine devices or condom) or has a vasectomised male partner. 2. Body mass index ≥30 kg/m2. If outside this range, eligible at investigator's discretion. 3. Waist circumference ≥102cm in men and ≥88cm in women. If outside this range, eligible at investigator's discretion. 4. Certain medications may be excluded based on investigators discretion. 5. Lives in the Perth Metropolitan Area. 6. Willing to change all they eat, not eat out and not wear makeup for 4 weeks if selected for intervention. 7. Ability to give written informed consent. 8. Proof of immunisation against COVID-19 (SARS-CoV-2), according to WA Health guidelines at time of recruitment. Exclusion Criteria: 1. Any abnormalities in electrocardiogram (ECG) readings, or as per the Investigator's discretion. 2. History of drug or alcohol abuse in the past 24 months. Alcohol abuse defined as greater than 21 units/week for males, greater than 14 units/week for females. 3. Current regular smoker or e-cigarette use. Social smokers (less than 3 nicotine/tobacco products in the last 3 months) can be included if abstaining for the duration of the study. 4. Currently pregnant or planning pregnancy during the course of the study as assessed by pregnancy testing carried out during screening. 5. Currently on, or within 3 months of discontinuing, glucagon-like peptide-1 agonists or related compounds. If inside this range, eligible at Investigator's discretion. 6. Living in a home that has been renovated in the past 4-weeks. 7. Have known severe food allergies or anaphylaxis to common food allergens. As per the Investigator's discretion. 8. Not suitable for the study for any other reason, as determined by the investigator. 9. Acute infection, surgery, vaccination, or other inflammatory process in the previous 2 weeks. Minor procedures are exempt at investigator's discretion. 10. Evidence of moderate or greater renal impairment at screening, as indicated by an estimated creatinine clearance of less than 60 mL/min using the Cockcroft-Gault equation. 11. Clinically significant abnormal laboratory tests or examination findings, as determined by the investigator, not otherwise mentioned.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Harry Perkins Institute of Medical Research
Nedlands, Western Australia, 6009, Australia
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