CARDIOMETABOLIC RISK FACTORS

This study is testing whether a low dose of the drug semaglutide can help obese adults lose weight and improve their heart health. The trial will include 60 Pakistani adults who are obese but do not have diabetes. Participants will receive weekly injections and lifestyle advice f…

This study tests whether vitamin D3 supplements can improve heart health in Chinese teenagers who are overweight or obese and have low vitamin D levels. 130 participants will receive either vitamin D3 or a placebo for 12 weeks. Researchers will measure changes in blood pressure, …

This study is testing whether a multi-strain probiotic supplement, taken alongside standard lifestyle advice, can improve liver health in people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The trial will enroll 80 adults with elevated liver enzymes and …

This study tests whether taking ginger capsules every day can lower markers of inflammation and oxidative stress in adults who are overweight. Researchers will measure changes in blood levels of substances linked to inflammation and heart health. The goal is to see if a simple di…

This study tests whether adding the diabetes drug empagliflozin to the standard heart medication carvedilol can prevent serious liver complications or death in people with cirrhosis and a stiff heart condition. About 400 adults aged 18-65 with cirrhosis and left ventricular diast…

This study looks at whether adding a special whey protein supplement to a high-fat meal can improve markers of heart and brain health in postmenopausal women who are overweight and at moderate risk for heart disease. Sixteen women will each try the supplement and a placebo on sep…

This study compares two simple physical activity strategies—short walks after meals and brief activity snacks—to standard 30-minute exercise sessions in breast and prostate cancer survivors. The goal is to see which approach best controls blood sugar and is easiest to fit into da…

This study tests whether drinking a ginger-based beverage every day can reduce inflammation and improve markers of heart health in adults with excess body fat. Researchers will measure changes in blood markers like interleukins and cholesterol. The study involves 50 participants …

This study looks for the smallest amount of movement needed to improve blood pressure and blood sugar when you sit for long periods. About 324 adults will test different break schedules in a lab. The goal is to create simple, effective guidelines for everyone.

This study tests five different group programs, all delivered remotely, to help adults with higher body weight eat healthy and be active. Some groups also include mindful eating, body image support, or finding enjoyable physical activities. The goal is to see which program people…