New study tests drug to stop 'Rebound Pain' after shoulder surgery
NCT ID NCT07642674
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving the anti-inflammatory drug dexketoprofen through a vein can prevent or lessen the severe pain that often occurs when a nerve block wears off after shoulder surgery. About 66 adults having arthroscopic shoulder surgery will be randomly assigned to receive either standard pain treatment or standard treatment plus dexketoprofen. Researchers will track pain scores and the amount of extra pain medicine needed in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dexketoprofen (a nonsteroidal anti-inflammatory drug)
- What this could lead to
- If it works, this could give doctors a simple way to prevent severe pain after shoulder surgery when the nerve block wears off.
- What could go wrong
- This is a small, early-stage study (66 people) and the drug may not reduce rebound pain significantly. NSAIDs also carry risks for some patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age 18-70 years ASA score of I-III Arthroscopic shoulder surgery Exclusion Criteria: Patients who do not wish to participate in the study Creatinine clearance \<50 mL/ min Patients for whom NSAID use is contraindicated due to heart failure, Patients with psychiatric or cognitive dysfunction that would impair their ability to assess visual analog scale (VAS) pain scores Patients for whom peripheral nerve block is contraindicated
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Eskisehir Osmangazi Universıty Faculty of Medicine
RECRUITINGEskişehir, Odunpazarı, 26040, Turkey (Türkiye)
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