Real-world data sought on T-DXd for hard-to-treat breast cancers

NCT ID NCT05573893

Recruiting now Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This study follows 800 adults with advanced HER2-positive, HER2-low, or HER2-ultralow breast cancer who are receiving the drug trastuzumab deruxtecan as part of their normal care in Germany. Researchers will track how long patients stay on treatment, their quality of life, and any side effects. The goal is to understand how well the drug works outside of controlled clinical trials.

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Contacts and locations

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Study contacts

Contact

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Locations

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Amberg, 92224, Germany
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Ansbach, 91522, Germany
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Apolda, 99510, Germany
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Aschaffenburg, 63739, Germany
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Augsburg, 86150, Germany
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Augsburg, 86156, Germany
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Bad Reichenhall, 83435, Germany
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Baden-Baden, 76532, Germany
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Balingen, 72336, Germany
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Bamberg, 96049, Germany
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Berlin, 10117, Germany
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Berlin, 10367, Germany
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Berlin, 10715, Germany
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Berlin, 12623, Germany
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Berlin, 13125, Germany
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Bielefeld, 33604, Germany
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Bonn, 53111, Germany
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Brandenburg an der Havel, 14770, Germany
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Braunschweig, 38100, Germany
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Bremen, 28209, Germany
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Bremerhaven, 27574, Germany
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Coburg, 96450, Germany
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Dessau, 6847, Germany
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Donauwörth, 86609, Germany
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Dortmund, 44137, Germany
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Dresden, 1127, Germany
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Dresden, 1307, Germany
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Düsseldorf, 40235, Germany
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Eggenfelden, 84307, Germany
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Erfurt, 99085, Germany
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Essen, 45147, Germany
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Filderstadt - Bonlanden, 70794, Germany
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Frankfurt, 60389, Germany
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Freudenstadt, 72250, Germany
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Fürstenfeldbruck, 82256, Germany
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Fürstenwalde, 15517, Germany
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Gerlingen, 70839, Germany
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Giessen, 35392, Germany
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Halle, 6110, Germany
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Hamburg, 20259, Germany
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Hamburg, 21073, Germany
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Hanover, 30161, Germany
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Hanover, 30449, Germany
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Hansestadt Salzwedel, 29410, Germany
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Heidenheim, 89522, Germany
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Heilbronn, 74078, Germany
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Hildesheim, 31134, Germany
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Homburg/Saar, 66421, Germany
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Jena, 7747, Germany
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Kaiserslautern, 67655, Germany
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Karlsruhe, 76135, Germany
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Kassel, 34117, Germany
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Kassel, 34125, Germany
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Kempten, 87439, Germany
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Kiel, 24116, Germany
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Krefeld, 47805, Germany
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Kulmbach, 95326, Germany
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Landshut, 84036, Germany
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Leer, 26789, Germany
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Leipzig, 4103, Germany
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Loerrach, 79539, Germany
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Lübeck, 23562, Germany
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Lüneburg, 21339, Germany
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Magdeburg, 39130, Germany
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Mainz, 55131, Germany
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Marburg, 35037, Germany
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Memmingen, 87700, Germany
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Mönchengladbach, 41061, Germany
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Mutlangen, 73557, Germany
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Mühlhausen, 99974, Germany
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München, 80638, Germany
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München, 80639, Germany
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München, 81377, Germany
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Neumarkt, 92318, Germany
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Neustadt am Rübenberge, 31535, Germany
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Nordhausen, 99734, Germany
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Nuremberg, 90419, Germany
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Oldenburg, 26121, Germany
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Oranienburg, 16515, Germany
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Potsdam, 14467, Germany
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Recklinghausen, 45659, Germany
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Regensburg, 93053, Germany
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Rosenheim, 83022, Germany
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Rotenburg (Wümme), 27356, Germany
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Saalfeld, 7318, Germany
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Saarbrücken, 66113, Germany
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Schwäbisch Hall, 74523, Germany
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Siegen, 57072, Germany
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Singen, 78224, Germany
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Solingen, 42653, Germany
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Stade, 21680, Germany
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Stuttgart, 70199, Germany
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Torgau, 4860, Germany
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Troisdorf, 53840, Germany
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Ulm, 89073, Germany
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Walsrode, 29664, Germany
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Weiden, 92637, Germany
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Weinheim, 69469, Germany
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Weißenfels, 6667, Germany
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Westerstede, 26655, Germany
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Wiesbaden, 65199, Germany
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Winnenden, 71364, Germany
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Witten, 58452, Germany
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Wolfsburg, 38440, Germany
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Wuppertal, 42283, Germany
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Würzburg, 97080, Germany
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Zittau, 02763, Germany

Conditions

Explore the condition pages connected to this study.

BREAST CANCER BREAST NEOPLASMS BREAST NEOPLASMS NEOPLASM METASTASIS