New Brain-Zapping therapy aims to boost recovery after severe head trauma
NCT ID NCT07373366
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a noninvasive treatment called REAC that uses gentle electrical signals to help rebalance brain activity after a severe traumatic brain injury. Researchers will compare real REAC sessions to a sham (fake) version in 60 patients to see if it improves brain wave patterns and daily function. The goal is to ease symptoms and support recovery, not to cure the injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * DAI diagnostic and consent for participation with the next of kin for each eligible patient Exclusion Criteria: * Open TBI * History of chronic neurological conditions
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital das Clínicas da FM-USP
RECRUITINGSão Paulo, São Paulo, 05.403-905, Brazil
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can group wellness classes improve life after brain injury or dementia?
- Can a web program rebuild memory after brain injury?
- Why a simple fall can cause brain bleeding in older adults
- Bedside ultrasound could flag hidden brain injury decline
- Zapping the brain to restore lost vision
- Machine learning may forecast brain decline after head injury