Second round of radiation may help fight recurrent brain cancer
NCT ID NCT06344130
First seen Jan 10, 2026 · Last updated Jun 22, 2026 · Updated 25 times
Summary
This early-phase trial tests a new way to give radiation to people whose glioblastoma (a severe brain cancer) has come back after initial treatment. About 28 adults will receive focused radiation over 1 to 3 weeks, depending on the dose level. The main goal is to find a safe schedule, while also tracking how long the tumor stays under control and quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Radiation therapy
What this could lead to
If successful, this could establish a safer way to give additional radiation to people whose brain tumor has returned, potentially extending survival.
What could go wrong
This is a very early phase 1 trial with only 28 participants, so it is primarily testing safety, not effectiveness. The benefits are uncertain, and there is a risk of brain damage from extra radiation.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.