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New nerve block may cut opioid use after kidney transplants

NCT ID NCT07716566

Symptom relief Sponsor: Kanuni Sultan Suleyman Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study tests whether a new ultrasound-guided nerve block called the quadroiliac plane block can reduce pain and opioid use after kidney transplant surgery better than the standard method of injecting anesthetic into the surgical wound. Sixty adults receiving a kidney transplant will be randomly assigned to one of the two pain-block techniques. Researchers will measure how much pain medication patients need in the first 24 hours after surgery, along with pain scores and recovery quality.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a nerve block procedure called ultrasound-guided quadroiliac plane block, compared with surgical wound infiltration, both using the anesthetic bupivacaine
What this could lead to
If the quadroiliac block works better, it could offer a more effective way to control pain after kidney transplant surgery and reduce the need for opioids.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to all patients. The block is a new technique and may not prove superior to the standard approach.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 80 years * American Society of Anesthesiologists physical status I-III * Scheduled to undergo renal transplantation surgery * Ability to understand the study procedures and postoperative assessments * Provision of written informed consent Exclusion Criteria: * Known allergy to bupivacaine or other amide-type local anesthetics * Infection at the planned injection site * Coagulopathy or anticoagulant therapy associated with an unacceptable bleeding risk for regional anesthesia * Sepsis * Severe spinal deformity or anatomical abnormality preventing performance of the quadroiliac plane block * Inability to cooperate or communicate reliably * Cognitive impairment or intellectual disability preventing informed consent or reliable outcome assessment * Altered level of consciousness * Breastfeeding * Refusal to participate

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Conditions

The condition(s) this trial relates to.

end stage renal failure Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital

    RECRUITING

    Istanbul, Istanbul, 34303, Turkey (Türkiye)

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