Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New gel may cut pain and bleeding after mouth surgery

NCT ID NCT05773781

Symptom relief Sponsor: University of Liverpool Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a gel called PuraBond, applied to the surgical wound during mouth or throat surgery, can reduce pain and bleeding afterward. 73 patients were randomly assigned to receive the gel or not. Researchers measured pain levels over 30 days and tracked complications like bleeding and hospital readmission.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
PuraBond (a gel-like 3-D matrix applied to the surgical wound)
What this could lead to
If it works, this gel could become a simple way to reduce pain and bleeding after mouth or throat surgery.
What could go wrong
This is a small, early-stage trial (73 people) and the results may not apply to everyone. The gel might not provide meaningful benefit over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

73 people

The number who actually took part.

Started

Oct 2023

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient and disease factors are deemed suitable for transoral surgery under general anaesthetic. * Decision to treat with primary transoral resection or local excision biopsy. * Written informed consent provided. * Clinically suspected or histologically confirmed primary dysplasia or malignancy of the oral cavity or oropharynx OR histologically confirmed diagnosis of squamous cell carcinoma in a cervical lymph node of unknown primary. * Patient considered fit for surgery. Exclusion Criteria: * Lesions undergoing incisional or punch biopsy only. * Surgery with planned primary closure or local/ distant flap reconstruction. * Inability to provide written informed consent. * Medical contraindication to a general anaesthetic or to PuraBond® use.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Hemorrhage are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Hemorrhage intraepithelial neoplasia metastatic squamous cell carcinoma oral cavity cancer oropharynx cancer Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemorrhage Hemostatics Oral cavity Oropharynx Pain

Contacts and locations

Locations

  • Liverpool University Hospitals Foundation Trust (LUHFT)

    Liverpool, L9 7AL, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.