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New study puts fluoxetine to the test for PTSD relief

NCT ID NCT05948553

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 28 times

Summary

This study tests whether fluoxetine, a standard antidepressant, can reduce PTSD symptoms in active-duty service members, veterans, and civilians. About 200 participants will receive either the drug or a placebo for 12 weeks, with researchers tracking changes in symptom severity and safety. The goal is to see if this existing medication can offer a new option for PTSD treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advanced Discovery Research

    Atlanta, Georgia, 30318, United States

  • Alexander T. Augusta Military Medical Center (ATAMMC):

    Fort Belvoir, Virginia, 22060-5285, United States

  • Cincinnati Veteran's Affairs Medical Center

    Fort Thomas, Kentucky, 41075, United States

  • Homestead Associates in Research, Inc.

    Miami, Florida, 33032, United States

  • Madigan Army Medical Center

    Joint Base Lewis McChord, Washington, 98433, United States

  • Tripler Army Medical Center (TAMC)

    Tripler AMC, Hawaii, 96859, United States

  • Upstate Clinical Research Associates, LLC

    Williamsville, New York, 14221, United States

  • Walter Reed National Military Medical Center (WRNMC)

    Bethesda, Maryland, 20889-5632, United States

  • Wilford Hall Ambulatory Surgical Center (WHASC)

    San Antonio, Texas, 78236, United States

Conditions

Explore the condition pages connected to this study.