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Could a blood injection ease Amputees' nerve pain?

NCT ID NCT07624890

Symptom relief Sponsor: Ukrainian Society of Regional Anesthesia and Pain Therapy Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two injection treatments for chronic nerve pain (neuroma) after combat-related amputation. One uses platelet-rich plasma (PRP) from the patient's own blood, the other uses a standard local anesthetic. About 100 adults with persistent pain will receive an ultrasound-guided injection and be followed for changes in pain, phantom limb pain, and daily function. The goal is to see if PRP offers longer-lasting relief than current temporary options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Combat-related limb amputation * Chronic neuroma pain lasting ≥3 months * Ultrasound-confirmed painful neuroma * Average neuroma pain intensity ≥4/10 on the Numeric Rating Scale * Persistent pain interfering with rehabilitation, prosthesis use, or daily activities * Ability to undergo ultrasound-guided injection * Stable analgesic regimen for at least 14 days before enrollment * Ability to provide written informed consent Exclusion Criteria: * Active infection at or near the injection site * Open wound preventing safe injection * Previous PRP injection for neuroma pain within 6 months * Previous neuroma surgery within 3 months * Severe coagulopathy or platelet disorder * Anticoagulant therapy contraindicating injection * Active malignancy * Severe uncontrolled systemic disease * Known allergy to local anesthetics * Inability to complete follow-up assessments

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Conditions

The condition(s) this trial relates to.

neuroma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neuroma Phantom limb pain after amputation Platelet rich plasma (PRP) Stump pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Feofaniya Clinical Hospital

    Kyiv, 03143, Ukraine

  • Vinnitsya university hospital

    Vinnytsia, 21000, Ukraine

More trials for these conditions

Other studies related to the condition(s) this trial covers.