Could a simple blood injection ease your back pain?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Age between 18 to 60 years * Patient with AD characterized by a common lumbar spine for more than 3 months associated with Modic I discopathy on MRI on a single level * Annulus fibrosus capable of holding the cell implantation, demonstrated by MRI (stages \< 5 of Pfirrmann's score). The Pfirrmann's score is fully described in annex (Pfirrmann et al. 2001). * Daily LBP for at least 3 month with baseline mean intensity ≥ 40 mm on VAS (0-100) in the previous 48 hours * Written and signed informed consent form * Subjects must be covered by public health insurance * Subjects must be able to attend all scheduled visits and to comply with all trial procedures Exclusion Criteria: * \- Patient with Modic 1 discopathy in different vertebral levels * Patient with a Modic I signal abnormality related to a static spinal disorder (such as previous vertebral fractures, or isthmic lysis, or spondyloarthritis) * Patient with a history of lumbar spine surgery * Patient with suspected spondylodiscitis or other infection * Patient under anticoagulant or antiaggregant therapy, or with a coagulation disorder * Patient with allergy to iodine or to any of the components of Xylocaine * Contraindication to MRI: Pacemaker or neurosensorial stimulator or implantable defibrillator, cochlear implant, ferromagnetic foreign body similar to the nervous structure. * Patient with anatomical difficulty of access to the injection area (judged by the investigator) * Patient with an uncontrolled severe disease (i.e. heart, pulmonary, gastro-intestinal, neurologic, endocrine, auto-immune affections) limiting the patient's safety (judged by the investigator) * Patient with previous malignancy less than 5 years (except for non-melanoma skin cancer) * Prior to the screening visit: * a current and recent use of morphine (\< 1 month) * a systemic or local corticosteroid therapy (\< 1 month) * Porphyria * Patient with sphincter disorders indicating a cauda equina syndrome * Psychotic state not controlled by a treatment * Pregnancy (βHCG positive), breast-feeding or the absence of effective contraception for women of child-bearing age * Vulnerable persons protected by law * Persons under guardianship * Subject who are in a dependency or employment with the sponsor or the investigator * Participation in another clinical trial * Subject unable to read or/and write