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Blood-Derived shot may mend Worn-Out knees

NCT ID NCT06082531

Disease control Sponsor: Xijing Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether injections of platelet-rich plasma (PRP) — a concentrate from a person's own blood — can repair knee osteoarthritis and injuries to cartilage, meniscus, and ligaments. Researchers will compare PRP against standard hyaluronic acid injections in 300 adults aged 20 to 60. The goal is to see if PRP improves joint structure and reduces damage better than current care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
platelet-rich plasma (PRP) injection
What this could lead to
If effective, PRP injections could offer a non-surgical option to repair knee cartilage and reduce pain from osteoarthritis.
What could go wrong
This is an early exploratory study, and PRP's benefits over standard treatments remain unproven. Results may vary by individual.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint. * The preoperative routine tests and examinations revealed no contraindications. * Revised sentence: "Informed consent of the patient Exclusion Criteria: * The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream. * Prolonged usage of anti-inflammatory drugs and systemic corticoid administration. * In injection site or damage to the skin. * Patients with tumors or undergoing radiotherapy and chemotherapy. * Pregnant or breastfeeding women. * Individuals with mental illnesses who are unable to cooperate with follow-up procedures. * Contraindications for MRI、Patients or their families do consent to participate in the study. * Other circumstances that render participation in the study unsuitable.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cartilage injury Meniscus disorder Osteoarthritis knees both Platelets-rich plasma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Xijing Hospital

    RECRUITING

    Xi'an, Shannxi, 710034, China

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