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Can your own blood heal a torn knee ligament?

NCT ID NCT07185802

Disease control Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether a single injection of platelet-rich plasma (PRP), made from the patient's own blood, can improve healing in people with partial anterior cruciate ligament (ACL) tears. Half of the 52 participants will get the injection plus standard rehab; the other half will get rehab alone. Researchers will measure pain and knee function over 16 weeks to see if PRP offers extra benefit.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
platelet-rich plasma (PRP) injection
What this could lead to
If it works, this could offer a simple, natural injection to improve healing and reduce pain for people with partial ACL tears, possibly avoiding surgery.
What could go wrong
This is a small, early-phase trial with only 52 people. PRP may not provide any extra benefit over standard rehab, and results may not apply to more severe injuries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 52 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Patients of both sexes who are older than 18 years and younger than 50 years * 3 or Less than 3-months history of knee injuries * ACL injury MRI Grade 1 (Low) and medium Grade 2 (Medium) grade * ACL injury associated with Grade 1 or 2 Posterior cruciate ligament (PCL) tear and/or Grade 1 or 2 meniscal tear * The Complete Blood Count (CBC) report shows a hemoglobin \> 10gm/dl and platelet count \>150,000/microliter prior to the procedure * Capable of comprehending informed consent Exclusion criteria: * Patients who have had intra articular corticosteroid injections in the index knee during the last 12 weeks * Patients who are taking systemic steroid * Patients who are younger than 18 and older than 50 years * Those with a history of platelet disorders or on the therapeutic anticoagulant or anti platelet drugs * Hemoglobin below 10 gm/dl * Platelet count \<150000/microliter * Complete tear of both bundles on MRI * Grade 3 or more PCL and meniscal tear on MRI * Previous or concurrent ligament reconstruction in the index knee joint. * Connective tissue disorders like Marfan Syndrome, Ehler-Danlos Syndrome etc. * Any inflammatory disease like Rheumatoid Arthritis, spondyloarthritis, gout, pseudogout etc involving the knee joint.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bangabandhu Sheikh Mujib Medical University

    RECRUITING

    Dhaka, 1000, Bangladesh

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