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Nerve block before ACL surgery could help teens recover faster

NCT ID NCT06875427

Symptom relief Sponsor: Isabella Jaramillo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a numbing injection (nerve block) given before ACL knee surgery helps teens recover better. About 38 participants aged 10-18 will either get the block plus standard anesthesia or standard anesthesia alone. Researchers will measure recovery quality, pain, opioid use, and satisfaction up to 6 weeks after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ropivacaine and dexmedetomidine
What this could lead to
If it works, this could show that a simple nerve block before ACL surgery helps teens recover faster with less pain and fewer opioids.
What could go wrong
This is a small feasibility trial with only 38 participants, so results may not apply to everyone. The block may not improve recovery and carries rare risks like nerve injury or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 38 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients ASA I, II and III * 10-18 years of age * scheduled for ACL reconstruction * agreeable to regional block and follow-ups Exclusion Criteria: * Contraindications to adductor canal block. * Patients with coagulopathies, preexisting neurologic deficit * Significant comorbidities that may impact recovery or interfere with the study. * Refusal to regional techniques. * Moderate to severe cognitive deficit (patients who are unable to complete the questionnaire) * Patients with history of malignant hyperthermia

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Conditions

The condition(s) this trial relates to.

Lacerations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament Anterior cruciate ligament (ACL) tear

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • McMaster Children's Hospital, Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8N 3Z5, Canada

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