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Can a simple test predict ACL tears in teen soccer stars?

NCT ID NCT07653633

Knowledge-focused Sponsor: Cardenal Herrera University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow 200 young male soccer players from Villarreal CF for up to 4 years to understand why some get ACL injuries. Researchers will analyze how they jump, their heart rate, genes, and gut bacteria. The goal is to create a tool that gives each player a personalized risk score, so coaches can tailor training to reduce injury risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a personalized risk score that helps coaches and trainers design exercises to prevent ACL injuries in athletes.
What could go wrong
This is an observational study, not a treatment trial. It only collects data to build a prediction model, so it won't directly prevent injuries. The model may not work for all athletes or sports.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The target population includes active athletes, both in developmental stages and at the professional level, participating in sports with a high risk of ACL injury, such as soccer, basketball, handball, and volleyball. These disciplines share biomechanical patterns involving jumping, deceleration, and changes of direction that impose high loads on the knee joint complex, justifying their selection for the development of predictive models applicable across different sports contexts.

Ages

10 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Active federation license with Villarreal CF during the study period. * Regular participation in training sessions and official competitions. * Aged between 10 and 45 years (encompassing academy, youth development, and first-team categories). * For participants under 18 years of age: mandatory written informed consent from a parent or legal guardian. * For minor participants aged ≥12 years: written informed assent must be provided by the athlete in addition to parental consent. Exclusion Criteria: * Previous bilateral anterior cruciate ligament (ACL) reconstruction. * Active severe musculoskeletal injury that prevents the execution of biomechanical or physiological testing. * Systemic disease or medical condition that limits sports participation or interferes with the study's biological/physiological parameters. * Deregistration or transfer to another sports club during the prospective follow-up period. Refusal or inability to comply with the protocol's testing procedures or long-term follow-up requirements.

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Conditions

The condition(s) this trial relates to.

injury Lacerations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament (ACL) Anterior cruciate ligament (ACL) tear

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Villareal Football Club

    Villarreal, Spain, 12540, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.