Can school programs curb teen drug use? cherokee nation trial seeks answers
NCT ID NCT04839978
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed trial tested two school-based programs—Connect and CMCA—to prevent drug and alcohol misuse among 10th graders in rural Cherokee Nation high schools. Over 900 students from 20 schools participated, with some schools receiving the programs and others serving as controls. The study tracked alcohol, marijuana, and opioid use over time to see if the programs made a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- school-based screening, brief intervention, and referral program
- What this could lead to
- If effective, this approach could reduce drug and alcohol misuse in rural Native American communities.
- What could go wrong
- The trial is completed but results are not yet widely known. The programs may not work for all teens or in other settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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919 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 to 17 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Tenth grade students enrolled in the participating high schools Exclusion Criteria: * unable to understand written or verbal English Inclusion criteria for high schools: * Counties that partially or fully fall within the Cherokee Nation reservation * Town population of 3,000 or less * Class size between 30 to 100 students Exclusion criteria for high schools: * Metropolitan and micropolitan cores (Rural-Urban Commuting Area codes of 1 and 4) * Existence of a community drug prevention coalition
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cherokee Nation Reservation
Tahlequah, Oklahoma, 74464, United States
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