New group care model aims to boost HIV prevention in sex workers
NCT ID NCT05929521
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage study tests a group healthcare model called Centering PrEP+ (C-PrEP+) to help sex workers take and stick with PrEP, a daily pill that prevents HIV. Instead of one-on-one visits, small groups meet with providers for health checks and interactive learning. The study enrolls 24 sex workers and clinic staff to see if this approach is feasible and acceptable.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Group PrEP Care (C-PrEP+)
- What this could lead to
- If successful, this group care model could make HIV prevention more accessible and effective for sex workers, potentially reducing HIV transmission in this community.
- What could go wrong
- This is a very early pilot study with only 24 participants, so results may not apply broadly. The intervention is behavioral, not a drug, so its impact on actual HIV rates is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
-
About 24 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Dec 2024
- Expected to finish
-
Dec 2025
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Howard Brown Health personnel Inclusion Criteria: 1. 18 years of age or older; 2. currently employed at Howard Brown Health 3. are active in HIV prevention programs, epidemiology and/or GTZ 2030 projects; 4. speak and understand English Howard Brown Health personnel Exclusion Criteria: 1. \<18 2. Not employed at Howard Brown Health 3. Not active in HIV prevention programs, epidemiology and/or GTZ 2030 projects 4. Does not speak and understand English Sex workers Inclusion Criteria: 1. Initiating PrEP at HBH 2. ≥ 18 years of age; 3. engaged in sex work, defined as the exchange of oral, vaginal, or anal sex for something of value, in the past 12 months; 4. lives in Chicago area; 5. speak/understand English. Sex Workers Exclusion Criteria: 1. Not initiating PrEP at HBH 2. \< 18 years of age; 3. Identify as a victim of sex trafficking 3\) Not engaged in sex work, defined as the exchange of oral, vaginal, or anal sex for something of value, in the past 12 months; 4) Does NOT live in Chicago area; 5) Does NOT speak/understand English. 6) Does not/cannot provide informed consent.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Pre-exposure prophylaxis are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Illinois at Chicago
Chicago, Illinois, 60612, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could nurses replace doctors for HIV prevention Check-Ups?
- Could a buddy system for HIV care improve lives?
- Counseling program aims to boost mental health and HIV prevention in young women
- Can a smartphone app help young black women cut alcohol and prevent HIV?
- Malawi study tests HIV prevention safety for moms and babies
- Can food vouchers and peer support keep women on HIV prevention pills?