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Can a simple wipe before surgery stop infections? new trial tests it

NCT ID NCT07508566

Disease control Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether using wipes with a special antibacterial solution (chlorhexidine gluconate) before surgery can reduce bacteria on the skin better than standard cleaning. It involves 40 men with urethral stricture who are scheduled for reconstructive surgery. Researchers will measure bacteria levels at key skin sites to see which method works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
2% chlorhexidine gluconate (CHG) wipes
What this could lead to
If successful, this could show that using CHG wipes before surgery lowers infection rates, leading to better recovery for men with urethral stricture.
What could go wrong
This is a small, early-stage study with only 40 participants, so results may not apply to everyone. It focuses on bacterial levels, not actual infection rates, so the real-world benefit is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Male patients aged ≥18 years with a clinically confirmed diagnosis of urethral stricture, who are scheduled to undergo lingual mucosal urethroplasty or end-to-end urethral anastomosis. Possess normal cognitive and communication abilities, and be able to cooperate with preoperative cleaning procedures and postoperative follow-up. No history of topical antimicrobial therapy on the perineal region before surgery, and no systemic antibiotic administration within 1 week prior to surgery. Voluntarily participate in this study and sign the informed consent form. Exclusion Criteria: Complicated with severe systemic infectious diseases, or suffering from immunodeficiency diseases (e.g., AIDS, long-term use of immunosuppressants). Presence of skin damage, ulcers, eczema or other dermatoses on the perineal skin, which may interfere with cleaning procedures and bacterial sample collection. A definite history of allergy to chlorhexidine gluconate (CHG) or study-related supplies. Having surgical contraindications such as severe hepatic and renal insufficiency, or coagulation dysfunction. Inability to cooperate with preoperative cleaning procedures, or failure to complete postoperative follow-up due to personal reasons

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Conditions

The condition(s) this trial relates to.

Surgical Wound Infection urethral stricture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Urethral stricture

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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