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Battle of the knives: which surgery wins for narrowed urethra?

NCT ID NCT07668973

Disease control Sponsor: Sahiwal medical college sahiwal Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study compares two surgical methods to repair a short (up to 2 cm) narrowing in the bulbar urethra. One technique removes the scarred section and reconnects healthy ends; the other uses a graft from the lining of the testicle to widen the stricture. 94 men aged 18-50 with non-traumatic strictures will be randomly assigned to one surgery and followed for 12 months to see which has fewer recurrences and complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
surgical procedure (excision and primary anastomosis urethroplasty or tunica vaginalis graft urethroplasty)
What this could lead to
If successful, this trial could show that one surgical technique is better than the other for treating short bulbar urethral strictures, potentially reducing recurrence and complications.
What could go wrong
This is a small, single-center trial that has not yet started recruiting. Results may not apply to all patients, and both surgeries carry risks like infection, graft failure, or erectile dysfunction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 94 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with diagnosis of bulbar urethral stricture upto 2cm in length. * Patients aged between 18-50 years. * Patients with non-traumatic bulbar urethral stricture. * Isolated short (≤ 2 cm) bulbar urethral stricture * Patient is able and willing to comply with the postoperative protocol. Exclusion Criteria: * Urethral stricture which is completely obliterated stricture. * Patients with history of hypospadias or previous open urethral surgery. * Patients with uncontrolled diabetes or Immunocompromised patients. * Patients unwilling for the follow-up. * History of pelvic radiation therapy * Patient with history of urethral instrumentation in last 3 months. * Lichen sclerosus related strictures. * Patients with history of erectile dysfunction, priapism or treatment to enhance erectile function.

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Conditions

The condition(s) this trial relates to.

erectile dysfunction urethral stricture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Erectile dysfunction Urethral stricture

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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