Can Pre-Surgery training improve recovery in gynecologic cancer?
NCT ID NCT07608445
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether a physiatry-led prehabilitation program—including exercise, nutrition, and mind-body practices—can help women with advanced gynecologic cancer stay stronger before surgery. Twenty-five participants will follow the program during their neoadjuvant treatment. The main goal is to see if it's feasible, not yet to prove it works.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- prehabilitation program (education, goal setting, rehabilitation, supportive care)
- What this could lead to
- If successful, this could show that starting physical and mental support before treatment helps patients recover better after surgery.
- What could go wrong
- This is a very small pilot study (25 people) testing feasibility, not effectiveness. It may not show clear benefits or be too demanding for patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 25 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * PATIENT: Documented informed consent of the participant * PATIENT: Willingness to comply with a physiatry consultation, start a tailored training program, and follow-up assessments * PATIENT: Age: ≥ 18 years * PATIENT: Able to read and write in English * PATIENT: A diagnosis of stage III-IVA gynecologic cancer planned for NST * PATIENT: Plan to start NST at City of Hope Orange County * HEALTHCARE TEAM: Documented informed consent of the participant * HEALTHCARE TEAM: Willingness to complete the Healthcare Worker Survey * HEALTHCARE TEAM: ≥ 18 years old * HEALTHCARE TEAM: Physicians, advanced practice providers, nurses, medical assistants, rehabilitation therapists, social workers, dietitians, mental health professionals, and other clinical staff who interact with study participants in the course of routine care Exclusion Criteria: * PATIENT: Current or planned cancer treatment for a second cancer * PATIENT: Clinically significant uncontrolled illness limiting participation with the research intervention and assessments * PATIENT: Stage IVB cancer with distant metastases * PATIENT: Other active malignancy * PATIENT: Pregnant or breastfeeding * PATIENT: Any other condition that would, in the Investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures * PATIENT: Meeting or exceeding exercise guidelines over the last one month based on the responses from the Godin-Shephard Leisure Time Physical Activity Questionnaire (GSLTPAQ) * PATIENT: Started second cycle before the physiatry consult * PATIENT: Inability to independently follow instructions for study assessments for any reason such as mental incapacitation or significant emotional or psychological disorder that, in the opinion of the investigators, precludes study entry. (These patients may not be able to cooperate with the prehabilitation interventions or with the data collection process.) * PATIENT: Unable to independently answer questionnaires in English * HEALTHCARE TEAM: Healthcare workers who do not interact with study participants and therefore cannot provide relevant feedback
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
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City of Hope at Irvine Lennar
Irvine, California, 92618, United States
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Other studies related to the condition(s) this trial covers.
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