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Exercise before ovarian cancer surgery may reduce frailty and boost recovery

NCT ID NCT05364879

Symptom relief Sponsor: Nova Scotia Health Authority Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 4-week exercise program before surgery can reduce frailty and improve recovery in women with advanced ovarian cancer. Frailty affects about half of these patients and often leads to worse surgical outcomes and chemotherapy delays. The program includes light-to-moderate aerobic, resistance, and mobility exercises done three times a week. Researchers will measure changes in frailty, surgical complications, and chemotherapy completion rates.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised exercise program (aerobic, resistance, and mobility exercises)
What this could lead to
If it works, this could show that a simple exercise program before surgery helps frail ovarian cancer patients recover faster and complete their chemotherapy as planned.
What could go wrong
This is a small, early-stage study (108 people) with no control group, so results may not be definitive. Exercise may be difficult for very frail patients, and benefits are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 108 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years or older * Have a confirmed diagnosis of stage III or IV ovarian cancer * Scheduled to receive cytoreductive surgery as part of their treatment plan * Must have a minimum of 4-weeks between the time of study enrollment and scheduled surgery * Be able to attend in-person and/or virtual exercise sessions * Be fluent in English * Have oncologist approval Exclusion Criteria: * Have already completed surgery * Unstable cardiac or respiratory disease, injury or any other co-morbid disease that may make it unsafe for participants to exercise * Significant cognitive impairment (e.g., do not have the capacity to consent, unable to follow exercise instructions)

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Conditions

The condition(s) this trial relates to.

Frailty Motor Activity ovarian cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Enhanced recovery after surgery Exercise Frailty Ovarian cancer Prehabilitation Surgical complication Treatment outcomes

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Nova Scotia Health

    RECRUITING

    Halifax, Nova Scotia, B3L 4P1, Canada

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