Custom ventilation may boost survival in lung failure patients
NCT ID NCT06066502
First seen May 23, 2026 · Last updated May 23, 2026
Summary
This study compares standard mechanical ventilation to a personalized, lung-stress oriented strategy in 1,100 adults with acute respiratory distress syndrome (ARDS). The goal is to see if tailoring the breathing machine settings to each patient can improve survival. Participants are randomly assigned to one of two ventilation approaches.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Albert Einstein College of Medicine/Montefiore Medical Center
RECRUITINGThe Bronx, New York, 10461, United States
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Atrium Health Wake Forest Baptist
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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Baylor College of Medicine / St. Luke's Medical Center
RECRUITINGHouston, Texas, 77030, United States
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Cedar-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Emory University / Grady Health System
NOT_YET_RECRUITINGAtlanta, Georgia, 30322, United States
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Intermountain Health
RECRUITINGMurray, Utah, 84107, United States
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Lowell General Hospital
NOT_YET_RECRUITINGLowell, Massachusetts, 01854, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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NYU Lagone Health
RECRUITINGNew York, New York, 02114, United States
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New York City Health + Hospitals/ Bellevue
RECRUITINGNew York, New York, 10016, United States
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Ohio State University Wexner Medical Center
RECRUITINGColumbus, Ohio, 43210, United States
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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Stanford University
RECRUITINGPalo Alto, California, 94305, United States
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Thomas Jefferson University
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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Tufts Medical Center
RECRUITINGBoston, Massachusetts, 02111, United States
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University of Arizona
RECRUITINGTucson, Arizona, 85724, United States
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University of Arkansas for Medical Sciences
RECRUITINGLittle Rock, Arkansas, 72205, United States
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University of California, Los Angeles Medical Center
RECRUITINGLos Angeles, California, 90024, United States
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University of California, San Diego
RECRUITINGLa Jolla, California, 92093, United States
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University of California, San Francisco
RECRUITINGSan Franciso, California, 94143, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Cincinnati
RECRUITINGCincinnati, Ohio, 45267, United States
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Oklahoma Health Sciences
NOT_YET_RECRUITINGOklahoma City, Oklahoma, 73104, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84132, United States
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22908, United States
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University of Washingont/Harborview Medical Center
RECRUITINGSeattle, Washington, 98104, United States
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Conditions
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