Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New MRI technique could sharpen cancer radiation targeting

NCT ID NCT04657042

Knowledge-focused Sponsor: University of Virginia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new imaging method called 4D-MRI that creates 3D movies of the lungs and liver as a person breathes. The goal is to help doctors better track tumor movement during radiation therapy, making treatment more precise. Researchers will test this in healthy volunteers and cancer patients to see if it outperforms current CT scans.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this imaging method could help doctors target tumors more precisely during radiation therapy, potentially improving treatment outcomes.
What could go wrong
This is an early-stage imaging study in healthy volunteers and a small number of cancer patients. The technique may not improve treatment planning as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2020

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Up to 30 lung cancer patients, 30 liver cancer patients, and 40 healthy human volunteers will receive MRI examinations at the University of Virginia to directly measure respiratory motion in the thorax and abdomen. All subject populations will include roughly equal male and female representations. The subject populations will have minority and ethnic representation typical of the local population area that includes the University of Virginia. No specific racial or ethnic group will be excluded. All subjects must have the ability to understand the requirements of the study and must provide informed consent with a personal signature. No persons from vulnerable populations will be included in this study.

Ages

18 to 82 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:The inclusion criteria for lung and liver cancer patients are: * Patient is 21 or older * Patient has primary or metastatic tumor(s) in the lungs or the liver * Diameter of the tumor(s) is less than 7 cm * Patient will receive radiation therapy (ordered by the treating Radiation Oncologist) as part of their treatment regimen * Patient will undergo a planning CT scan with tumor motion assessment (planning 4D-CT ordered by the treating Radiation Oncologist) as part of their treatment regimen * Patient has signed informed consent and is willing to comply with the 4D-MRI imaging protocol The inclusion criteria for healthy volunteers are: * Subject is 18 or older * Subject has signed informed consent and is willing to comply with the 4D-MRI imaging protocol Exclusion Criteria: * Any condition for which a MRI procedure is contraindicated including presence of metallic material in the body, such as pacemakers, non- MRI compatible surgical clips, shrapnel, etc. * Subjects who have difficulty lying flat on their back for extended periods of time * Patients with any serious/poorly controlled medical or psychological conditions that would complicate protocol compliance * Too large to adequately fit in the magnet bore or RF coils * Claustrophobia * Females who are pregnant or lactating * Presence of active or chronic infection

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Healthy volunteers are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

liver cancer Liver Neoplasms lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers Liver cancer Lung cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22908, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.