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Tailored methadone may cut opioid risks for seniors after heart surgery

NCT ID NCT05612399

First seen Sep 30, 2025 · Last updated Jun 16, 2026 · Updated 29 times

Summary

This study aims to see if giving methadone based on a person's genes can reduce side effects like breathing problems, nausea, and sedation while still controlling pain after heart surgery. It will include 400 adults over 60 years old. Researchers will track pain levels, opioid use, and patient-reported outcomes to find the safest and most effective approach.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Presbyterian Hospital

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.