New hope for HIV patients battling depression: drug showdown begins
NCT ID NCT06705478
First seen Dec 08, 2025 · Last updated May 25, 2026 · Updated 26 times
Summary
This study compares two medications, pramipexole and escitalopram, to see which works better for treating major depression in people with HIV. About 186 participants will take one of the drugs for several weeks, and researchers will track mood changes and side effects. The goal is to find a safer, more effective way to ease depression symptoms in this group.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alabama CRS
RECRUITINGBirmingham, Alabama, 35222, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Barranco CRS
NOT_YET_RECRUITINGLima, 15063, Peru
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Blantyre CRS
NOT_YET_RECRUITINGBlantyre, 265, Malawi
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Byramjee Jeejeebhoy Medical College (BJMC) CRS
NOT_YET_RECRUITINGPune, Maharashtra, 411001, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Case CRS
NOT_YET_RECRUITINGCleveland, Ohio, 44106, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chapel Hill CRS
RECRUITINGChapel Hill, North Carolina, 27599-7215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS
NOT_YET_RECRUITINGChiang Mai, 50200, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cincinnati CRS
RECRUITINGCincinnati, Ohio, 45267-0405, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia Physicians & Surgeons (P&S) CRS
NOT_YET_RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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De La Salle Medical and Health Sciences Institute - Angelo King Medical Research Center (DLSMHSI-AKMRC)
NOT_YET_RECRUITINGDasmariñas, Cavite, 4114, Philippines
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Durban International CRS
NOT_YET_RECRUITINGMount Edgecombe, 4302, South Africa
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Gaborone CRS
NOT_YET_RECRUITINGGaborone, Botswana
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Greensboro CRS
RECRUITINGGreensboro, North Carolina, 27401-1020, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hanoi Medical University (HMU)
NOT_YET_RECRUITINGHanoi, 10000, Vietnam
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Harbor University of California, Los Angeles Center CRS
RECRUITINGTorrance, California, 90502, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Houston Advancing Research Team CRS
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS
NOT_YET_RECRUITINGRio de Janeiro, 21040-900, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Instituto de Pesquisas em AIDS do Rio Grande do Sul - IPARGS CRS
NOT_YET_RECRUITINGPorto Alegre, Rio Grande do Sul, 91350-180, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Joint Clinical Research Centre (JCRC)/Kampala CRS
NOT_YET_RECRUITINGKampala, Uganda
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS
NOT_YET_RECRUITINGKericho, Rift Valley, 20200, Kenya
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital CRS (MGH CRS)
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Milton Park CRS
NOT_YET_RECRUITINGMilton Park, Harare, Zimbabwe
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Moi University Clinical Research Center (MUCRC) CRS
NOT_YET_RECRUITINGEldoret, Rift Valley, 30100, Kenya
Contact Phone: •••-•••-•••• Email: •••••@•••••
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New Jersey Medical School Clinical Research Center CRS (Site ID 31786)
RECRUITINGNewark, New Jersey, 07103, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northwestern University CRS
NOT_YET_RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nutrición-Mexico CRS
NOT_YET_RECRUITINGMexico City, Tlalpan, 14080, Mexico
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ohio State University CRS
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Penn Therapeutics CRS
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Thai Red Cross AIDS Research Centre (TRC-ARC) CRS
NOT_YET_RECRUITINGPathum Wan, Bangkok, 10330, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Ponce de Leon Center CRS
RECRUITINGAtlanta, Georgia, 30308-2012, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCSD Antiviral Research Center CRS
RECRUITINGSan Diego, California, 92103, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California, Los Angeles CARE Center CRS
RECRUITINGLos Angeles, California, 90035, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California, San Francisco HIV/AIDS CRS
RECRUITINGSan Francisco, California, 94110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Colorado Hospital CRS
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh CRS
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Rochester Adult HIV Therapeutic Strategies Network CRS
NOT_YET_RECRUITINGRochester, New York, 14642, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt Therapeutics (VT) CRS
NOT_YET_RECRUITINGNashville, Tennessee, 37204, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University Therapeutics (WT) CRS
RECRUITINGSt Louis, Missouri, 63110-1010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Weill Cornell Chelsea CRS
NOT_YET_RECRUITINGNew York, New York, 10010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Weill Cornell Uptown CRS
NOT_YET_RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Whitman-Walker Institute, Inc. CRS
RECRUITINGWashington D.C., District of Columbia, 20009, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.