Could a Parkinson's drug help treat a key symptom of depression?
NCT ID NCT05355337
First seen Apr 28, 2026 · Last updated Jun 17, 2026 · Updated 15 times
Summary
This study tested whether pramipexole, a drug used for Parkinson's disease, can help people with depression who still have trouble feeling pleasure or motivation despite taking standard antidepressants. 85 adults with depression and significant anhedonia took either pramipexole or a placebo alongside their usual medication for 9 weeks. The goal was to see if the drug could improve anhedonia symptoms and help move toward more personalized depression treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Region Skåne
Lund, Skåne County, 221 85, Sweden
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