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New antibiotic cocktail aims to delay preterm birth after water breaks early

NCT ID NCT06396078

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This study tests whether a 7-day course of three antibiotics (ceftriaxone, clarithromycin, metronidazole) can prolong pregnancy and improve outcomes for pregnant individuals whose water breaks early (before 34 weeks). About 56 participants will be randomly assigned to the new combination or the current standard antibiotics. The goal is to delay delivery and reduce serious complications for newborns.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Medical Branch

    RECRUITING

    Galveston, Texas, 775555, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.