Which reversal drug causes fewer bathroom problems after surgery?
NCT ID NCT06948409
First seen Jan 25, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study reviewed records of 70,000 adults who had non-urinary surgery under general anesthesia. It compared two drugs used to reverse muscle relaxants: sugammadex and neostigmine (given with atropine or glycopyrrolate). The goal was to see which drug is linked to fewer cases of postoperative urinary retention, which can delay discharge from the recovery room. The study also looked at costs and unplanned hospital visits.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sugammadex or neostigmine (with atropine or glycopyrrolate)
What this could lead to
If this study finds one reversal drug causes less urinary retention, it could help doctors choose the safer option for patients after surgery.
What could go wrong
This is a retrospective study, meaning it looks back at past records, so it cannot prove cause and effect. Other factors could influence the results.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.