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Polyphenol power: grape & apple extract may boost exercise in thin air

NCT ID NCT07518758

Knowledge-focused Sponsor: Nexira Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a supplement called Vinitrox™, made from grape and apple polyphenols, can improve blood vessel function and exercise performance in healthy adults during moderate exercise in low-oxygen (hypoxic) conditions. 38 physically active volunteers will take either the supplement or a placebo before an exercise session. Researchers will measure blood vessel dilation, oxygen levels, and exercise output to see if the supplement provides any benefit.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vinitrox™ (polyphenol supplement from grape and apple extracts)
What this could lead to
If it works, this could point toward a natural supplement that helps athletes or people in low-oxygen environments perform better and maintain healthy blood vessel function.
What could go wrong
This is a small, early-stage trial in healthy volunteers, not patients. The effects may be minor or not translate to real-world performance. As a dietary supplement, it is not a treatment for any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 38 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * BMI \< 27 * Abdominal circumference \< 94 cm * Stable exercise training program during past 2 months Exclusion Criteria: * Total weekly exercise sessions \< 4 hours OR \> 8 hours * Drug or supplement intake during past one month that could interfere with study parameters * Volunteer suffering of respiratory or pulmonary condition * Volunteer exposed to an altitude \> 2000 meters during at least 3 weeks for the past 6 months.

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Conditions

The condition(s) this trial relates to.

Aneurysm Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise Healthy adult Healthy adults Vasodilation

Contacts and locations

Locations

  • Centre expertise de la performance Gilles Cometti

    Dijon, 21000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.