Polyphenol power: grape & apple extract may boost exercise in thin air
NCT ID NCT07518758
First seen Apr 12, 2026 · Last updated Jun 19, 2026 · Updated 13 times
Summary
This study tests whether a supplement called Vinitrox™, made from grape and apple polyphenols, can improve blood vessel function and exercise performance in healthy adults during moderate exercise in low-oxygen (hypoxic) conditions. 38 physically active volunteers will take either the supplement or a placebo before an exercise session. Researchers will measure blood vessel dilation, oxygen levels, and exercise output to see if the supplement provides any benefit.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centre expertise de la performance Gilles Cometti
Dijon, 21000, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vinitrox™ (polyphenol supplement from grape and apple extracts)
What this could lead to
If it works, this could point toward a natural supplement that helps athletes or people in low-oxygen environments perform better and maintain healthy blood vessel function.
What could go wrong
This is a small, early-stage trial in healthy volunteers, not patients. The effects may be minor or not translate to real-world performance. As a dietary supplement, it is not a treatment for any disease.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.