Polyphenol power: grape & apple extract may boost exercise in thin air

NCT ID NCT07518758

First seen Apr 12, 2026 · Last updated Jun 19, 2026 · Updated 13 times

Summary

This study tests whether a supplement called Vinitrox™, made from grape and apple polyphenols, can improve blood vessel function and exercise performance in healthy adults during moderate exercise in low-oxygen (hypoxic) conditions. 38 physically active volunteers will take either the supplement or a placebo before an exercise session. Researchers will measure blood vessel dilation, oxygen levels, and exercise output to see if the supplement provides any benefit.

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Contacts and locations

Locations

  • Centre expertise de la performance Gilles Cometti

    Dijon, 21000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vinitrox™ (polyphenol supplement from grape and apple extracts)

What this could lead to

If it works, this could point toward a natural supplement that helps athletes or people in low-oxygen environments perform better and maintain healthy blood vessel function.

What could go wrong

This is a small, early-stage trial in healthy volunteers, not patients. The effects may be minor or not translate to real-world performance. As a dietary supplement, it is not a treatment for any disease.

Conditions

The condition(s) this trial relates to.

Aneurysm Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.