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New hope for hard-to-treat prostate cancer: experimental drug combo enters human trials

NCT ID NCT06785636

First seen Nov 17, 2025 · Last updated May 23, 2026 · Updated 31 times

Summary

This study tests a new drug called pocenbrodib, either alone or with other treatments, in people with a type of advanced prostate cancer that no longer responds to standard hormone therapy. The goal is to find the safest dose and see if it can shrink tumors or lower PSA levels. About 252 adults with metastatic disease will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer and Blood Research Center

    RECRUITING

    Los Alamitos, California, 90720, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Community Health Network

    RECRUITING

    Indianapolis, Indiana, 46250, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University medical center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

    Contact Phone: •••-•••-••••

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Karmanos Cancer Institute

    RECRUITING

    Detroit, Michigan, 48201, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MemorialCare Orange Coast Medical Center

    RECRUITING

    Fountain Valley, California, 92708, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mount Sinai Medical Center

    RECRUITING

    Miami, Florida, 33140, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Oncology - Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-••••

    Contact

  • Nebraska Cancer Specialists

    RECRUITING

    Omaha, Nebraska, 68130, United States

    Contact Phone: •••-•••-••••

    Contact

  • Ochsner

    RECRUITING

    Jefferson, Louisiana, 70121, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oncology Consultants, P.A

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact

  • Siteman Cancer Center

    RECRUITING

    St Louis, Missouri, 63108, United States

    Contact Phone: •••-•••-••••

    Contact

  • Taylor Cancer Research Center

    RECRUITING

    Maumee, Ohio, 43537, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado Health

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.