Heart surgery upgrade: zap away bad rhythms while implanting pump
NCT ID NCT05034432
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 25 times
Summary
This study tests whether destroying small areas of heart muscle that cause dangerous rhythms (ventricular tachycardia ablation) during LVAD implant surgery can reduce the number of these rhythms after surgery. About 100 adults with advanced heart failure who are getting an LVAD will be randomly assigned to either receive the ablation during surgery or standard care. The main goal is to see if the ablation lowers the total number of dangerous heart rhythm events.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CARDIOMYOPATHIES are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-••••
Locations
-
Ascension St. Vincent Indianapolis
RECRUITINGIndianapolis, Indiana, 46260, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Banner University Medical Center
RECRUITINGPhoenix, Arizona, 85006, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact
Contact Phone: •••-•••-••••
-
Columbia University Medical Center
RECRUITINGNew York, New York, 10026, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Henry Ford Health
RECRUITINGDetroit, Michigan, 48202, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Medstar Washington Hospital Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Piedmont Heart Institute
RECRUITINGAtlanta, Georgia, 30309, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Tufts Medical Center
RECRUITINGBoston, Massachusetts, 02111, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
UCLA Cardiac Arrthmia Center
RECRUITINGLos Angeles, California, 90095, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
UPMC
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Univedrsity of Louisville
RECRUITINGLouisville, Kentucky, 40202, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Rochester
RECRUITINGRochester, New York, 14642, United States
Contact
Contact
-
Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Intra-operative ventricular tachycardia ablation (a procedure to destroy small areas of heart muscle that cause abnormal rhythms)
What this could lead to
If it works, this could reduce dangerous heart rhythms after LVAD surgery, potentially lowering hospitalizations and improving recovery.
What could go wrong
This is a phase 4 trial with only 100 participants, so results may not apply to everyone. The ablation itself carries risks like bleeding or damage to the heart.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.