New study checks if PICC lines harm vein walls
NCT ID NCT07466472
First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 2 times
Summary
This study looks at how a PICC line (a thin tube placed in a vein for long-term medicine) affects the health of the vein wall. Researchers will measure vein thickness before and after the tube is removed in 80 adults who need a PICC. They will also test a special system that helps guide the tube to the right spot. The goal is to make PICC placement safer and understand any changes it causes to veins.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients (\>18years) with sinus rhythm in the absence of an implanted cardiac pacing device and a medical indications for PICC placement, including oncologic therapy, parenteral nutrition, or prolonged intravenous treatment, will be considered eligible for participation. All participants will provide written informed consent prior to enrollment.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * sinus rhythm * medical indication * suitable upper-extremity venous anatomy confirmed by ultrasound examination * ability to provide written informed consent Exclusion Criteria: * Implanted cardiac pacing device * Palliative care * \<18years old * Local infection, skin lesion, or burn at the intended insertion site * Severe coagulopathy contraindicating vascular access procedures * Known allergy to catheter materials or local anesthetics used during the procedure * Presenceof an implanted cardiac pacemaker or non-sinus cardiac rhythm preventing reliable intracavitary ECG guidance * Anatomical abnormalities preventing safe PICC insertion * Previous lymphadenectomy on the intended side * Pre-existing venous thrombosis or significant venous wall pathology detected on baseline ultrasound
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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