Needle showdown: one vs two for safer IV lines
NCT ID NCT07594704
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two different methods (one-needle vs two-needle) for placing a PICC line, a long-term IV used for treatments like chemotherapy. About 284 adults who need a PICC for the first time will take part. The goal is to find out which method leads to fewer complications like bleeding, infection, or blood clots.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 284 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged between 18 and 75 years old; * Educational level of primary school or above, with basic listening, speaking, reading and writing abilities, and capable of completing the questionnaire independently; * Receiving tunneled PICC catheterization for the first time, with 4Fr single-lumen solo PICC catheter indwelling; * Able to attend regular PICC maintenance at our hospital as scheduled after catheterization; * Voluntarily participate in this study and sign the informed consent form for this study as well as the informed consent form for PICC catheterization. Exclusion Criteria: * Patients with coagulation dysfunction (INR \> 1.5 / PLT \< 50×10⁹/L); * Pregnant or lactating women; * Patients with BMI \< 18.5 kg/m²; * Patients receiving PICC catheterization via lower extremity veins; * Patients with known or suspected allergy to components of PICC catheters.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510000, China
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