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Laser zaps bad breath in gum disease study

NCT ID NCT06764342

Symptom relief Sponsor: Federal University of Minas Gerais Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a special laser treatment (photodynamic therapy) to standard gum cleaning could reduce bad breath. Forty adults with gum disease and self-reported bad breath received full-mouth scaling plus a laser-activated gel on their tongue and deep gum pockets. The researchers measured sulfur gases and bacteria levels before and after treatment to see if the laser made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
methylene blue gel and red laser
What this could lead to
If it works, this could offer a new, quick way to reduce bad breath for people with gum disease.
What could go wrong
This is a small, completed trial with only 40 people. Results may not apply to everyone, and the effect might be small or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2025

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * self-reported halitosis; * organoleptic score \>2; * stage III periodontitis; * at least 14 teeth. Exclusion Criteria: * smokers or former smokers; * individuals diagnosed with diabetes and/or immune diseases; * pregnant or lactating women; * individuals with removable partial dentures and/or fixed or removable orthodontic appliances; * systemic use of antibiotics or anti-inflammatory drugs in the last three months; - individuals who required prophylactic antibiotics for periodontal exams and treatments; * individuals who regularly used or had used any type of mouthwash in the past three months; * individuals who underwent periodontal treatment in the six months prior to the study.

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Conditions

The condition(s) this trial relates to.

Halitosis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Halitosis Periodontitis

Contacts and locations

Locations

  • Federal University of Minas Gerais, Dental School

    Belo Horizonte, Minas Gerais, 31270-901, Brazil

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