Light before the knife: could a laser zap prevent wisdom tooth swelling?
NCT ID NCT05924191
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests whether shining a low-intensity laser on the gums and face an hour before wisdom tooth extraction can lessen the swelling, pain, and jaw stiffness that follow. Thirty adults with impacted lower wisdom teeth will receive either the light treatment or a placebo pill. Researchers will measure facial swelling, pain levels, and how well the jaw opens at 2 and 7 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a low-intensity laser device (photobiomodulation) applied inside the mouth and on the face before surgery
- What this could lead to
- If effective, this light-based approach could offer a drug-free way to reduce swelling and pain after wisdom tooth surgery, speeding recovery.
- What could go wrong
- This is a small, early-stage trial with only 30 participants. The effect may be modest or no better than placebo, and results may not apply to other types of surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
30 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Jul 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who present retained lower third molars, according to the degree of surgical difficulty of the procedure and the anatomical position.The selected molars will be those classified according to classes II and III and/or B or C of Pell and Gregory Classification; in vertical or mesio-angular position, according to the Winter Classification or Class II with need for ostectomy or III, with need for ostectomy and odontosection of the Prant Scale, modified by Amarillas-Escobar et al. * That have an indication for the extraction of the lower third molars (due to recurrent infections, bad anatomical position, orthodontic indication) or a professional indication presented in writing and that are healthy (ASA I, with a negative medical history). * Male or female gender. * Age between 18 and 50 years. * Good oral hygiene. * That they agree to participate in the study, after reading and signing the Informed Consent for participation in clinical research. Exclusion Criteria: * Carriers of local alterations that contraindicate surgical intervention or complicate the postoperative period (example: acute phase pericoronitis in the last 30 days, ankylosis of the temporomandibular joint). * Smokers, * Presenting absence of upper and lower central incisors, * With a medical history of photosensitivity * During pregnancy or lactation, * That they were using anti-inflammatories or analgesics, * Allergic to any of the drugs used in the research (amoxicillin, ketorolac, acetaminophen, dexamethasone, chlorhexidine 2%, local anesthetics, sodium bisulfite, etc.) * That during surgery they present any type of complication (bleeding, transoperative difficulties, etc.), because these cases are not included within the expected pattern behavior for this type of surgery (these cases will be reported), * Surgical time greater than 90 minutes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kristianne Porta Santos Fernandes
São Paulo, São Paulo, 01525-000, Brazil
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Other studies related to the condition(s) this trial covers.
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