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New imaging agent could spot hidden infections

NCT ID NCT07110519

First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 33 times

Summary

This early-phase study tests a new radioactive tracer called [18F]-fluoromannitol in 10 healthy adults. The goal is to see if it is safe and how it spreads through the body during a PET scan. If all goes well, this tracer might one day help doctors find infections in people with conditions like sickle cell disease or cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[18F]-fluoromannitol (a radioactive tracer for PET scans)

What this could lead to

If successful, this tracer could help doctors spot infections in people with sickle cell disease, cancer, or joint implants using PET scans.

What could go wrong

This is a very early, small study in just 10 healthy people. It only checks safety and distribution, not whether the tracer actually works for detecting infections.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.