PET scan could sharpen radiation for returning brain tumors
NCT ID NCT05653635
First seen Feb 04, 2026 · Last updated Jun 19, 2026 · Updated 19 times
Summary
This phase II trial tests whether using a special PET scan (FDOPA-PET) to guide radiation therapy can help people with recurrent glioblastoma, an aggressive brain cancer. About 54 participants who have already had radiation will receive a more precise radiation boost to active tumor spots. The main goal is to see if this approach delays tumor regrowth at the treated site.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHRU de Nancy
NOT_YET_RECRUITINGNancy, De, 5400, France
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Centre Paul Strauss
RECRUITINGStrasbourg, 67033, France
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy guided by FDOPA-PET scan
What this could lead to
If successful, this approach could improve how long patients with recurrent glioblastoma stay free of tumor regrowth after re-irradiation.
What could go wrong
This is a small, early-phase trial (54 people) and may not show a clear benefit. The treatment involves radiation, which can cause side effects like brain swelling or damage to healthy tissue.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.