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Personalized tablet activities may boost brain training in seniors with mild cognitive impairment

NCT ID NCT03292705

Symptom relief Sponsor: University of Rochester Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a personalized computer program (PEP) could improve attitudes toward technology and engagement with cognitive training in 49 older adults with mild cognitive impairment living in senior communities. Participants first used PEP or a control activity for 4 weeks, then all completed 6 weeks of standard cognitive training. The goal was to see if personalized, enjoyable computer use could make subsequent brain training more effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Personalized Engagement Program (PEP) – a tablet-based system with tailored leisure activities
What this could lead to
If it works, this approach could make cognitive training more engaging and effective for older adults with mild memory problems.
What could go wrong
This is a small, early proof-of-concept study with only 49 participants. Results may not apply to everyone, and the benefits may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

49 people

The number who actually took part.

Started

Oct 2017

Finished

Sep 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 ≤ MoCA ≤ 26 * RAVLT Delayed Recall Total Score ≤ 6 (or 1.5 SD below age-corrected norms) * mild or no active depressive symptoms * intact or mild deficits in IADL functioning * if on AD medication (i.e., Memantine or cholinesterase inhibitors), antidepressant, or anxiolytics, no changes of doses in the 3 months prior to recruitment; * age ≥60 years * English-speaking * adequate visual and hearing acuity for testing * intact decision making capacity. Exclusion Criteria: * current enrollment in another cognitive improvement study; * uncontrollable major depression: or other psychopathology identified by staff or medical records; * having active legal guardian (indicating impaired capacity for decision making); * medical history of AD or other types of dementia

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mild cognitive impairment

Contacts and locations

Locations

  • Brickstone/Saint John Meadow

    Rochester, New York, 14618, United States

  • River Edge Manor

    Rochester, New York, 14642, United States

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