Blood pressure experiment in sepsis halted early – kidney protection still unclear
NCT ID NCT01473498
First seen May 19, 2026 · Last updated Jun 22, 2026 · Updated 6 times
Summary
This study tested whether raising the blood pressure target from 65 mmHg to 85 mmHg in patients with septic shock could help prevent kidney injury. Researchers used a drug called norepinephrine to adjust blood pressure and monitored kidney function. The trial was stopped early and only included 27 participants, so no firm conclusions can be drawn.
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
-
Reanimation Chirurgicale - Hôpital Kremlin Bicêtre
Le Kremlin-Bicêtre, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
norepinephrine
What this could lead to
If successful, this approach could point toward a personalized way to manage blood pressure in septic shock to reduce kidney damage.
What could go wrong
The trial was terminated early and enrolled only 27 people, so results are very limited. It is unclear if targeting a higher blood pressure is safe or effective.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.