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New nerve block could replace standard pain injection for hip surgery

NCT ID NCT05898581

Symptom relief Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether a nerve block called PENG block can control pain after hip replacement as well as the usual method of injecting numbing medication into the surgical area. Sixty adults getting hip replacement will be randomly assigned to one of the two pain relief methods. Researchers will measure pain scores and muscle strength after surgery to see if the nerve block is a good alternative.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine (a numbing medication) and a nerve block procedure (PENG block)
What this could lead to
If the nerve block works as well as the standard injection, it could offer a better pain control option for hip replacement patients, especially those who cannot take opioids or NSAIDs.
What could go wrong
This is a small pilot study with only 60 people, so results may not apply to everyone. The nerve block is a newer technique with limited data, and it may not control pain as effectively as the standard method.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patient (\>18 years old) 2. Undergoing THA with a direct lateral surgical approach (transgluteal approach) 3. Ability to provide verbal/written consent to participate in this trial Exclusion Criteria: 1. Patient with any contraindication for spinal anesthesia 2. Patient with any contraindication for regional analgesia 3. Patient undergoing THA with a direct anterior surgical approach 4. Patients undergoing THA for hip revision 5. Patients undergoing THA under One Day Stay (ODS) admission 6. Patients that received opioids intrathecally 7. Patients having residual motor block six hours after the completion of the spinal anesthesia. 8. Patients with a history of regular opioid intake for more than three months 9. Patients incapable of performing knee extension of the same operative side 10. Pregnant patients

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia

How to take part

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  1. The places running it

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  2. The official record

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    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • London Health Sciences Centre

    RECRUITING

    London, Ontario, Canada

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