Immuno-chemo combo shrinks bladder tumors before surgery in early trial
NCT ID NCT02690558
First seen Jan 31, 2026 · Last updated May 24, 2026 · Updated 16 times
Summary
This study tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemotherapy (gemcitabine and cisplatin) could shrink tumors more effectively before bladder cancer surgery. 39 adults with muscle-invasive bladder cancer received the combination before having their bladder removed. The main goal was to see how many patients had their cancer stage reduced to below stage 2 at the time of surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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North Carolina Cancer Hospital (UNC)
Chapel Hill, North Carolina, 27599, United States
Conditions
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