Immunotherapy boosts chemo before bladder removal
NCT ID NCT02690558
First seen Jan 31, 2026 · Last updated May 14, 2026 · Updated 12 times
Summary
This study tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemotherapy (gemcitabine and cisplatin) could shrink tumors more effectively before bladder removal surgery in people with muscle-invasive bladder cancer. 39 participants received the combination before surgery. The main goal was to see how many had their cancer stage reduced to below stage 2 at the time of surgery. Results showed promising tumor shrinkage, but ongoing monitoring is needed as the cancer may still return.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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North Carolina Cancer Hospital (UNC)
Chapel Hill, North Carolina, 27599, United States
Conditions
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