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New combo attack on rare bladder cancer shows promise in early trial

NCT ID NCT04383743

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 30 times

Summary

This pilot study tested whether giving a combination of immunotherapy (pembrolizumab) and chemotherapy before surgery could help people with rare types of muscle-invasive bladder cancer. 17 participants received the treatment to see if it could eliminate all signs of cancer at the time of surgery. The goal was to improve outcomes compared to chemotherapy alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

Conditions

The condition(s) this trial relates to.

infiltrating bladder urothelial carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.